| Location | Effect |
| A | Your Kill Streak timer duration and reward bonus are doubled. |
| B | Pools of Reflection last for the entire Season and are not removed by death. |
| C | Items have no level requirement. |
| D | +200 Damage |
| E | +25% Missile Damage Reduction |
| F | +25% Movement Speed (Uncapped) |
| G | Increase damage against elites by 15%. |
| H | Picking up Health Globes grants a shield for 5% of your maximum health for 7 seconds. Max stacks 5. |
| I | +25% Melee Damage Reduction. |
| J | Increases your highest elemental skill damage bonus by 10%. |
| K | Increase damage against elites by 20%. |
| L | +20% Damage |
| M | Double the amount of Death's Breaths that drop. |
| N | Critical hits grant resource: Mana: 15, Hatred: 5, Wrath: 5, Arcane Power: 3, Fury: 3, Spirit: 5, Essence: 5. |
| O | Double the amount of Bounty Caches that drop from completing bounties. |
| P | Progress orbs from Nephalem and Greater Rifts are automatically picked up within 60 yards. |
| Q | Reduces the damage taken from elites by 25%. |
| R | +30 % Damage |
| S | Gain immunity to crowd-controlling effects. |
| T | Gain passability. |
| U | Pets pick up Death's Breath. |
| V | Elite packs drop one additional progress orb. |
| W | Increase damage done to Bosses by 25%. |
| X | Pets pick up and salvage common, magic, and rare items. |
| Y | Increase your chance to Dodge by 15%. |
| Z | Double the chance to find a legendary item purchased from Kadala. |
| Potion AA | When you drink your health potion, you manifest one of three runic circles on the ground that grant increased damage, increased cooldown reduction, or increased resource cost reduction. |
| Potion AB | When you drink your health potion, all enemies within 25 yards deal 25% less damage. |
| Potion AC | When you drink your health potion, gain a random shrine or the Dimensional Power pylon effect. |
| AD | When a primal item drops, a second random primal item drops as well. |
| Power # | Items Sacrificed |
| 1 | 10 Reusable Parts |
| 2 | Flawless Diamond (or greater), 15 Arcane Dust, 20 Resuable Parts |
| 3 | 1 Greater Rift Key, 10 Death's Breaths |
| 4 | Any Class Specific Set Helm |
| 5 | 20 Forgotten Souls, 10 Khanduran Runes, 10 Caldeum Nightshade, 10 Arreat War Tapestry, 10 Corrupted Angel Flesh, 10 Westmarch Holy Water |
| 6 | 1 Leoric's Regret, 1 Vial of Putridness, 1 Idol of Terror, 1 Heart of Fright |
| 7 | Reaper's Wraps |
| 8 | 30 Forgotten Souls |
| 9 | 1,100 Bloodshards (requires Greater Rift Solo 60 for capacity) |
| 10 | 1 Flawless Royal Ruby, 20 Death's Breaths, Ring of Royal Grandeur |
| 11 | 1 Flawless Royal Emerald, 30 Khanduran Runes, 30 Caldeum Nightshade, 30 Arreat War Tapestry, 30 Corrupted Angel Flesh, 30 Westmarch Holy Water |
| 12 | 20 Greater Rift Keys, 1 Ramaladni's Gift |
| 13 | 1,300 Bloodshards (requires Greater Rift Solo 80 for capacity) |
| 14 | Petrified Scream |
| 15 | Challenge Rift Cache |
| 16 | 250 Forgotten Souls |
| 17 | 1,400 Bloodshards (requires Greater Rift Solo 90 for capacity) |
| 18 | Ancient Hellfire Amulet |
| 19 | Four Tome of Set Dungeon Pages from your class. |
| 20 | Ancient Puzzle Ring, 50 Khanduran Runes, 50 Caldeum Nightshade, 50 Arreat War Tapestry, 50 Corrupted Angel Flesh, 50 Westmarch Holy Water |
| 21 | 500 Death's Breaths, 300 Forgotten Souls |
| 22 | 1,500 Bloodshards (requires Greater Rift Solo 100 for capacity) |
| 23 | Whisper of Atonement Rank 125 |
| 24 | Any Augmented Weapon |
| 25 | Staff of Herding |
| 26 | 1,600 Bloodshards (requires Greater Rift Solo 110 for capacity) |
| Potion 1 | 55 Primordial Ashes |
| Potion 2 | 110 Primordial Ashes |
| Potion 3 | 165 Primordial Ashes |
